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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRF1 All Species: 23.64
Human Site: S657 Identified Species: 40
UniProt: Q92994 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92994 NP_001510.2 677 73840 S657 E D G E P C V S A L Q M M G S
Chimpanzee Pan troglodytes XP_510208 819 88957 S799 E D G E P C V S A L Q M M G S
Rhesus Macaque Macaca mulatta XP_001098066 599 65136 A580 D G E P C V S A L Q M M G G N
Dog Lupus familis XP_548005 637 70371 A618 D G E P C V S A L Q M M G S N
Cat Felis silvestris
Mouse Mus musculus Q8CFK2 676 73781 S656 E D G E P C V S A L Q M M G G
Rat Rattus norvegicus NP_001100231 686 74096 S666 E D G E P C V S A L Q M M G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421405 681 75256 S661 E E D D H C M S A L Q L M G G
Frog Xenopus laevis NP_001088063 660 73751 S641 E E E E H C V S A L Q L M G G
Zebra Danio Brachydanio rerio NP_956183 693 76806 S673 E A E E S C V S A M E L I G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650616 662 73627 L643 E A T L Q D M L N T G G D D D
Honey Bee Apis mellifera XP_623775 648 73504 G629 M T V G E M L G H H G S E N E
Nematode Worm Caenorhab. elegans NP_495526 759 84015 K726 A K A K P N L K P I K Q K T A
Sea Urchin Strong. purpuratus XP_794011 768 83924 Q748 D H L Q S A A Q L M G H R G D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29056 596 66888 L577 A D S V K N M L Q K A S F S K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.3 86.4 82.7 N.A. 89.8 81.6 N.A. N.A. 78.1 72.5 65.9 N.A. 42.5 43.4 32.4 46.3
Protein Similarity: 100 80 87 85.9 N.A. 93.3 86 N.A. N.A. 87 84.7 77.6 N.A. 59.6 61.7 50 60.1
P-Site Identity: 100 100 13.3 6.6 N.A. 93.3 93.3 N.A. N.A. 53.3 66.6 46.6 N.A. 6.6 0 6.6 6.6
P-Site Similarity: 100 100 33.3 26.6 N.A. 93.3 93.3 N.A. N.A. 80 80 73.3 N.A. 13.3 6.6 40 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 15 8 0 0 8 8 15 50 0 8 0 0 0 8 % A
% Cys: 0 0 0 0 15 50 0 0 0 0 0 0 0 0 0 % C
% Asp: 22 36 8 8 0 8 0 0 0 0 0 0 8 8 15 % D
% Glu: 58 15 29 43 8 0 0 0 0 0 8 0 8 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 15 29 8 0 0 0 8 0 0 22 8 15 65 36 % G
% His: 0 8 0 0 15 0 0 0 8 8 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % I
% Lys: 0 8 0 8 8 0 0 8 0 8 8 0 8 0 8 % K
% Leu: 0 0 8 8 0 0 15 15 22 43 0 22 0 0 0 % L
% Met: 8 0 0 0 0 8 22 0 0 15 15 43 43 0 0 % M
% Asn: 0 0 0 0 0 15 0 0 8 0 0 0 0 8 15 % N
% Pro: 0 0 0 15 36 0 0 0 8 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 8 0 0 8 8 15 43 8 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % R
% Ser: 0 0 8 0 15 0 15 50 0 0 0 15 0 15 15 % S
% Thr: 0 8 8 0 0 0 0 0 0 8 0 0 0 8 0 % T
% Val: 0 0 8 8 0 15 43 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _